Publications
- Rojas, A.; Ganesh, T.; Zahra, M.; O’Neill, T.; Dingledine, R. Inhibition of the prostaglandin E2 receptor EP2 prevents status epilepticus induced deficits in the novel object recognition task in rats. Neuropharmacology. 2016, 110,419-430.
- Rojas, A.; Ganesh, T.; Walker, A.; Dingledine, R. Ethylatropine bromide, a peripherally restricted muscarinic antagonist. ACS Chem Neurosci. 2017, 8, 712-717.
- Ganesh, T.; Jiang, J.; Yang, M-S.; Dingledine, R. Lead optimization studies of cinnamic amide EP2 antagonists. J. Med. Chem., 2014, 57, 4173-4184
- Ganesh, T.; Jiang, J.; Dingledine, R. Development of second generation EP2 antagonists with high selectivity. Eur. J. Med. Chem. 2014, 82, 521-535
- Ganesh, T. Prostanoid receptor EP2 as a therapeutic target (a perspective article). J. Med. Chem. 2014, 57, 4454-4465
- Ganesh, T.; Jiang, J.; Shashidharamurthy, R.; Dingledine, R. Discovery and characterization of carbamothioylacrylamides as EP selective antagonists. ACS Med. Chem. Lett. 2013, 4, 616-621.
- Jiang, J.; Ganesh, T.; Du, Y.; Quan Y.; Serrano, G.; Qui, M.; Speigel, I.; Rojas, A.; Lelutiu, N.; Dingledine, R. Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2. Proc. Natl. Acad. Sci. 2012, 109, 3149-3154
- Ganesh. T. Improved Biochemical Strategies for Targeted Delivery of Taxoids (Review). Bioorg. Med. Chem. 2007, 15, 3597-3623
- Ganesh, T.; Guza, R. C.; Bane, S.; Ravindra, R.; Shanker, N.; Lakdawala, A. S; Snyder, J. P.; Kingston, D. G. The Bioactive Taxol Conformation on b-tubulin: Experimental Evidence from Highly Active Constrained Analogs. Proc. Natl. Acad. Sci. 2004, 101, 10006-10011.
For more publications click the link https://www.ncbi.nlm.nih.gov/pubmed