* Chin L-S. & Li, L. (2016) Ubiquitin phosphorylation in Parkinson's disease: Implications for pathogenesis and treatment. Transl. Neurodegener. 5:1 Epub 2016 Jan. 6. PMCID: PMC4702311 Transl. Neurodegener.

* Klionsky, D. J., Abdelmohsen, K., Abdalla, F.C., Abedin, M. J., ... Li, L. ..et al (2016) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 12:1-222 Autophagy

* Lee, S. M., Chin L-S., & Li, L. (2016) Dysregulation of ErbB receptor trafficking and signaling in demyelinating Charcot-Marie-Tooth disease. Mol. Neurobiol.  Epub 2016 Jan. 5 Mol. Neurobiol.

* Yung, C., Sha, D.,Li, L., & Chin L-S. (2015) Parkin protects against misfolded SOD1 toxicity by promoting its aggresome formation and autophagic clearance. Mol. Neurobiol.  Epub 2015 Nov. 13. Mol. Neurobiol.

* Fallaize, D.V., Chin, L-S., & Li, L. (2015) Differential submitochondrial localization of PINK1 as a molecular switch for mediating distinct mitochondrial signaling pathways.Cell Signal. 27: 2543-2554. PMCID: PMC4684445 Cell Signal.

* McKeon, J., Sha, D.,Li, L., and Chin L-S. (2015) Parkin-mediated K63-polyubiquitination targets ubiquitin C-terminal hydrolase L1 for degradation by the autophagy-lysosome system.  Cell. Mol. Life Sci.  72:1811-1824.  (Epub. 2014 Nov. 18)Cell. Mol. Life Sci.

* Chin L-S., Lee, S. M., and Li, L. (2013) SIMPLE: a new regulator of endosomal trafficking and signaling in health and disease. Commun Integr Biol. 6: e24214. Commun Integr Biol

* Lee, S. M., Sha, D., Mohammed, A.A., Asress, S., Glass, J.D., Chin L-S., and Li, L. (2013) Motor and sensory neuropathy due to myelin infolding and paranodal damage in a transgenic mouse model of Charcot-Marie-Tooth disease type 1C. Hum Mol Genet. 22:1755-1770. PMCID: PMC3613163 Hum Mol Genet.

** Lee, S. M., Chin L-S., and Li, L. (2012) Therapeutic implications of protein homeostasis in demyelinating peripheral neuropathies.  Expert Rev. Neurother. 12: 1041-1043. PMCID: PMC4312697.

*Hurst-Kennedy J, Chin LS, and Li L (2012) Ubiquitin C-Terminal Hydrolase L1 in Tumorigenesis. Biochem. Res. Int. 2012: 123706 Biochem. Res. Int.

* Klionsky, D. J., Abdalla, F.C., Abeliovich, H., ... Li, L. ..et al (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8: 445-544. Autophagy

* Lee, S. M., Chin L-S., and Li, L. (2012) Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking.  J. Cell Biol. 199: 799-816. J. Cell Biol.

* Lee SM, Chin LS, and Li L (2012) Protein misfolding and clearance in demyelinating peripheral neuropathies: therapeutic implications. Commun. Integral. Biol. 5(1):107-110Commun. Integral. Biol.

* Lee SM, Olzmann JA, Chin LS, and Li L. (2011) Mutations associated with Charcot-Marie-Tooth disease cause SIMPLE protein mislocalization and degradation by the proteasome and aggresome-autophagy pathways. J Cell Sci. 2011 Oct 1;124(Pt 19):3319-31. Epub 2011 Sep 6. J Cell Sci

* Olzmann, J. A., Chin L-S., and Li, L. (2010) The ubiquitin-proteasome system and the aggresome-autophagy pathway: Intersecting mechanisms of misfolded protein clearance in neurodegenerative disease.  In Ubiquitin Proteasome System in the Central Nervous System: From Physiology To Pathology.  Book Series: Biochemistry Research Trends.  Edited by M. Di Napoli and C. Wojcik.  Pages: 271-302

* Chen, J. , Li, L., and Chin, L.-S. (2010) Parkinson disease protein DJ-1 converts from a zymogen to a protease by carboxyl-terminal cleavage. Hum. Mol. Genet. 19(12):2395-408 PDF file

* Sha, D.,Chin, L.-S., and Li, L. (2010) Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-kB signaling. Hum. Mol. Genet. 19: 352-363. PDF file 

* Chin, L-S., Olzmann, J. A., and Li, L. (2010) Parkin-mediated ubiquitin signaling in aggresome formation and autophagy. Biochem. Soc. Trans. 38: 144-149. PDF file

* Giles, L.M., Li, L., and Chin, L-S. (2009) Printor, a novel torsinA-interacting protein implicated in dystonia pathogenesis. J. Biol. Chem. 284: 21765-21775. PDF file 

* Pridgeon, J. W., Webber, E. A., Sha, D., Li, L., and Chin, L.-S. (2009) Proteomic analysis reveals Hrs UIM-mediated ubiquitin signaling in multiple cellular processes. FEBS J. 276: 118-131. PDF file

* Giles, L.M. Li, L., and Chin, L.-S. (2009) TorsinA protein degradation and autophagy in DYT1 dystonia. Autophagy 5: 82-84. PDF file

* Whatley, B.R., Li, L., and Chin, L.-S. (2008) The ubiquitin-proteasome system in spongiform degenerative disorders. Biochim. Biophys. Acta - Molecular Basis of Disease. 1782: 700-712. PDF file

* Webber, E. A., Li, L., and Chin, L-S. (2008) Hypertonia-associated protein Trak1 is a novel regulator of endosome-to-lysosome trafficking. J. Mol. Biol. 382: 638-651. | PDF file

* Giles, L.M., Chen, J., Li, L., and Chin, L-S. (2008) Dystonia-associated mutations cause premature degradation of torsinA protein and cell-type specific mislocalization to the nuclear envelope. Hum. Mol. Genet. 17: 2712-2722 | PDF file 

* Olzmann, J. A., Chin L-S. and Li, L. (2008) The ubiquitin-proteasome system and the aggresome-autophagy pathway: Intersecting mechanisms of misfolded protein clearance in neurodegenerative disease. In The Ubiquitin Proteasome System in the Central Nervous System. Edited by M. Di Napoli and C. Wojcik. Nova Science Publishers, Inc.

* Olzmann, J. A., Li, L., and Chin, L.-S. (2008) Aggresome formation and neurodegenerative diseases: therapeutic implications. Curr. Med. Chem. 15: 47-60 |PDF file 

* Klionsky, D. J., Abeliovich, H., Agostinis, P., Agrawal, D. K., Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y, Chin, L.-S. et al (2008) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 4: 151-75. PDF file 

* Olzmann, J. A. and Chin L.-S. (2008) Parkin-mediated K63-linked polyubiquitination: A signal for targeting misfolded proteins to the aggresome-autophagy pathway. Autophagy 4: 85-87 | PDF file 

* Lee, J. T., Wheeler, T. C., Li, L., and Chin, L.-S. (2008) Ubiquitination of a-synuclein by Siah-1 promotes a-synuclein aggregation and apoptotic cell death. Hum. Mol. Genet. 17: 906-917. | PDF file 

* Djukic, B., Casper, K. B., Philpot, B. D., Chin, L.-S., and McCarthy, K. D. (2007) Conditional knockout of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation. J. Neurosci. 27:11354-11365 | PDF file 

* Olzmann, J. A., Li, L., Chudaev, M. V., Chen, J., Perez, F. A., Palmiter, R. D and Chin L.-S. (2007) Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6. J. Cell Biol. 178:1025-1038 | PDF file 

* Pridgeon, J. W., Olzmann, J. A., Chin, L.-S., and Li, L. (2007) PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1. PLoS Biology: 5(7): e172 | PDF file

* Kim, B., Olzmann, J. A., Barsh, G. S., Chin, L.-S., and Li, L. (2007) Spongiform neurodegeneration-associated E3 ligase mahogunin ubiquitylates TSG101 and regulates endosomal trafficking. Mol. Biol. Cell. 18: 1129–1142 | PDF file 

* Olzmann, J. A., Bordelon, J. R., Muly, E. C., Rees, H. E., Levey, A. I., Li, L., and Chin L.-S. (2007) Selective enrichment of DJ-1 in primate striatal neuronal processes: Implications for Parkinson's disease. J. Comp. Neurol. 500: 585-599. | PDF file 

* Li, L. and Chin, L.-S. (2007) Impairment of the ubiquitin-proteasome system: A common pathogenic mechanism in neurodegenerative disorders. In The Ubiquitin Proteasome System in the Central Nervous System: From Physiology to Pathology. Edited by M. Di Napoli and C. Wojcik. Nova Science Publishers, Inc. | PDF file

* Kirk, E. A., Chin, L.-S., and Li, L. (2006) GRIF1 binds Hrs and is a new regulator of endosomal trafficking. J. Cell Sci. 119: 4689-4701 | PDF file 

* Choi, J., Sullards, M. C., Olzmann, J. A., Rees, H. D., Weintraub, S. T., Bostwick, D. E., Gearing, M., Levey, A. I., Chin, L.-S., and Li, L. (2006) Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer Diseases. J. Biol. Chem. 281: 10816-10824 | PDF file

* Choi, J., Rees, H. D., Weintraub, S. T., Levey, A. I., Chin, L.-S., and Li, L. (2005) Oxidative modifications and aggregation of Cu/Zn superoxide dismutase associated with Alzheimer's and Parkinson's diseases. J. Biol. Chem. 280: 11648-11655 | PDF file

* Choi, J., Levey, A. I., Weintraub, S. T., Rees, H. D., Gearing, M., Chin, L.-S., and Li, L. (2004) Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases. J Biol Chem. 2004. 279, 13256-13264 | PDF file

* Olzmann, J.A., Brown, K., Wilkinson, K. D., Rees, . H. D., Huai, Q., Ke H., Levey, A. I., Li, L., and Chin, L.-S. (2004) Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function. J. Biol. Chem. 279, 8506-8515 | PDF file

* Huai, Q., Sun, Y., Wang, H., Chin L.-S., Li, L., Robinson, H. and Ke, H. (2003) Crystal structure of DJ-1/RS and implication on familial Parkinson's disease . FEBS Lett. 549: 171-175 | PDF file 

* Li, L. and Chin, L.-S. (2003) The molecular machinery of synaptic vesicle exocytosis. Cell. Mol. Life Sci. 60, 942-960 | PDF file

* Chin, L.-S., Vavalle, J. P., and Li, L. (2002) Staring, a novel E3 ubiquitin-protein ligase that targets syntaxin 1 for degradation. J. Biol. Chem. 277, 35071-35079 | PDF file 

* Li, Y., Chin, L.-S., Levey, A. I., and Li, L. (2002) Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking. J. Biol. Chem. 277, 28212-28221 | PDF file 

* Wheeler, T. C., Chin, L.-S., Li, Y., Roudabush, F. L., and Li, L. (2002) Regulation of synaptophysin degradation by mammalian homologues of seven in absentia. J. Biol. Chem. 277, 10273-10282 | PDF file 

* Ahn, K., Yeyeodu, S., Collette, J., Madden, V., Arthur, J., Li, L., and Erickson, A. H. (2002) An alternate targeting pathway for procathepsin L in mouse fibroblasts. Traffic 3, 147-159 | PDF file

* Li, Y., Chin, L.-S., Weigel, C., and Li, L. (2001) Spring, a novel RING finger protein that regulates synaptic vesicle exocytosis, J. Biol. Chem. 276, 40824-40833 | PDF file 

* Chin, L.-S., Raynor, M. C., Wei, X., Chen, H., and Li, L. (2001) Hrs interacts with sorting nexin 1 and regulates degradation of epidermal growth factor receptor, J. Biol. Chem. 276, 7069-7078 | PDF file

* Kwong, J., Roundabush, F. L., Moore, P. H., Montague, M., Oldham, W., Li, Y., Chin, L.-S., and Li, L. (2000) Hrs interacts with SNAP-25 and regulates Ca(2+)-dependent exocytosis, J. Cell Sci. 113, 2273-2284 | PDF file

* Chin, L.-S., Nugent, R. D., Raynor, M. C., Vavalle, J. P., and Li, L. (2000) SNIP, a novel SNAP-25-interacting protein implicated in regulated exocytosis, J. Biol. Chem. 275, 1191-1200 | PDF file

* Chin, L.-S., Weigel, C., and Li, L. (2000) Transcriptional regulation of gene expression of Sec6, a component of mammalian exocyst complex at the synapse, Brain Res. Mol. Brain Res. 79, 127-137 | PDF file 

* Walaas, S. I., Hilfiker, S., Li, L., Chin, L.-S., and Greengard, P. (2000) Decrease in phorbol ester-induced potentiation of noradrenaline release in synapsin I-deficient mice, Synapse 36, 114-119 | PDF file

* Chin, L.-S., Fu, Q., Kachinsky, A. M., Jabren, G., Niu, Y., and Li, L. (1999) Neuron-specific and developmental regulation of the synapsin II gene expression in transgenic mice, Brain Res. Mol. Brain Res. 67, 239-246 | PDF file

* Ferreira, A., Chin, L.-S., Li, L., Lanier, L. M., Kosik, K. S., and Greengard, P. (1998) Distinct roles of synapsin I and synapsin II during neuronal development, Mol. Med. 4, 22-28 | PDF file

* Ferreira, A., Li, L., Chin, L.-S., Greengard, P., and Kosik, K. S. (1996) Postsynaptic element contributes to the delay in synaptogenesis in synapsin I-deficient neurons, Mol. Cell. Neurosci. 8, 286-299 | PDF file

* Ryan, T. A., Li, L., Chin, L.-S., Greengard, P., and Smith, S. J. (1996) Synaptic vesicle recycling in synapsin I knock-out mice, J. Cell Biol. 134, 1219-1227 | PDF file 

* Chin, L.-S., Li, L., Ferreira, A., Kosik, K. S., and Greengard, P. (1995) Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice, Proc. Natl. Acad. Sci. U. S. A. 92, 9230-9234 | PDF file

* Li, L., Chin, L.-S., Greengard, P., Copeland, N. G., Gilbert, D. J., and Jenkins, N. A. (1995) Localization of the synapsin II (SYN2) gene to human chromosome 3 and mouse chromosome 6, Genomics 28, 365-366 | PDF file 

* Li, L., Chin, L.-S., Shupliakov, O., Brodin, L., Sihra, T. S., Hvalby, O., Jensen, V., Zheng, D., McNamara, J. O., Greengard, P., and et al. (1995) Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice, Proc. Natl. Acad. Sci. U. S. A. 92, 9235-9239 | PDF file 

* Lee, Y. H., Li, L., Lasalde, J., Rojas, L., McNamee, M., Ortiz-Miranda, S. I., and Pappone, P. (1994) Mutations in the M4 domain of Torpedo californica acetylcholine receptor dramatically alter ion channel function, Biophys. J. 66, 646-653 | PDF file

* Chin, L.-S., Li, L., and Greengard, P. (1994) Neuron-specific expression of the synapsin II gene is directed by a specific core promoter and upstream regulatory elements, J. Biol. Chem. 269, 18507-18513 | PDF file

* Li, L., Suzuki, T., Mori, N., and Greengard, P. (1993) Identification of a functional silencer element involved in neuron-specific expression of the synapsin I gene, Proc. Natl. Acad. Sci. U. S. A. 90, 1460-1464 | PDF file

* Eterovic, V. A., Li, L., Ferchmin, P. A., Lee, Y. H., Hann, R. M., Rodriguez, A. D., and McNamee, M. G. (1993) The ion channel of muscle and electric organ acetylcholine receptors: differing affinities for noncompetitive inhibitors, Cell. Mol. Neurobiol. 13, 111-121 | Abstract

* Eterovic, V. A., Hann, R. M., Ferchmin, P. A., Rodriguez, A. D., Li, L., Lee, Y. H., and McNamee, M. G. (1993) Diterpenoids from Caribbean gorgonians act as noncompetitive inhibitors of the nicotinic acetylcholine receptor, Cell. Mol. Neurobiol. 13, 99-110 |Abstract

* Li, L., and McNamee, M. G. (1992) Modulation of nicotinic acetylcholine receptor channel by pH: a difference in pH sensitivity of Torpedo and mouse receptors expressed in Xenopus oocytes, Cell. Mol. Neurobiol. 12, 83-93 | Abstract

* Li, L., Lee, Y. H., Pappone, P., Palma, A., and McNamee, M. G. (1992) Site-specific mutations of nicotinic acetylcholine receptor at the lipid-protein interface dramatically alter ion channel gating, Biophys. J. 62, 61-63 | PDF file

* Palma, A., Li, L., Chen, X. J., Pappone, P., and McNamee, M. (1991) Effects of pH on acetylcholine receptor function, J. Membr. Biol. 120, 67-73 | Abstract

* Ochoa, E. L., Li, L. A., Plummer, A., and McNamee, M. G. (1990) Direct effects of thymopentin (Arg-Lys-Asp-Val-Tyr) on cholinergic agonist-induced slow inactivation of nicotinic acetylcholine receptor function, Mol. Pharmacol. 38, 863-871 | PDF file

* Eterovic, V. A., Li, L., Palma, A., and McNamee, M. G. (1990) Regulation of nicotinic acetylcholine receptor function by adenine nucleotides, Cell. Mol. Neurobiol. 10, 423-433 | Abstract

* Li, L., Schuchard, M., Palma, A., Pradier, L., and McNamee, M. G. (1990) Functional role of the cysteine 451 thiol group in the M4 helix of the gamma subunit of Torpedo californica acetylcholine receptor, Biochemistry 29, 5428-5436 | PDF file

* Ochoa, E. L., Li, L., and McNamee, M. G. (1990) Desensitization of central cholinergic mechanisms and neuroadaptation to nicotine, Mol. Neurobiol. 4, 251-287 | Abstract