Under minimal supervision, performs a variety of specialized and complex research and laboratory tests and procedures. Uses independent judgment in applying or adapting scientific techniques. May assist in protocol design. Investigates and proposes alternative experimental procedures for consideration by a principal investigator. Assists in planning and scheduling research procedures. Analyzes and interprets results of studies. Demonstrates and trains others in the proper use/operation of laboratory techniques and equipment. Calibrates, troubleshoots and performs routine repair and maintenance of equipment. Reviews literature for related research developments and techniques and compiles findings. Monitors laboratory processes to maintain quality assurance standards. Records results of studies, compiles and analyzes data and prepares charts and graphs. Monitors the handling, storage and disposal of hazardous substances. Performs related responsibilities as required. Employees in this classification may be required to work with, take specific precautions against and/or be immunized against potentially hazardous agents.
Bachelor's degree in a scientific field and two years of research experience, or equivalent combination of experience, education, and training.
The Kukar lab uses a multi-disciplinary approach spanning chemistry, biology, and neuroscience to study neurodegeneration and dementia. A postdoctoral fellowship and laboratory technician position is available to study the etiology of Alzheimer's disease (AD), with the ultimate goal to translate these findings into new therapies. The primary project will focus on the mechanism of drugs called gamma-secretase modulators and their use in the treatment of AD (see Kukar et al., 2008 for more information). Other projects investigating therapeutic strategies for frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are also ongoing.
My laboratory is looking for dedicated individuals that are team players and self-motivated. The successful candidate should be a hard and efficient worker that wants to contribute towards human health while having fun doing cutting edge science. Candidates with expertise in three or more of the following areas are encouraged to apply: molecular biology, cell and tissue culture, immunocytochemistry, immunoprecipitation, high-throughput screening, Western blotting, proteomics, pharmacology, chemical biology, peptide/organic synthesis, transgenic animal models, animal surgery and behavioral testing, neuropathology, and neuroscience research. Multiple peer-reviewed publications and excellent verbal and written communication skills in English are a must. Individuals with a Ph.D. or M.D./Ph.D. are eligible for the postdoctoral fellowship. Individuals with a B.S. or M.S. are eligible for the technician position.