Hannah Wilkins, BSc

Education:

• BS., Biology and B.A., Hispanic Literature and Cultures, The University of North Carolina at Chapel Hill, Chapel Hill, NC

Description of research project:
I'm studying HIV antiretroviral drug disposition, metabolism, and transport in the brain, colon, and at the blood brain barrier using a variety of mass spectrometry techniques and cell-based assays.

Honors and Awards:

1. Institute for Basic Biomedical Sciences Fellowship, Johns Hopkins University
2. 2nd place poster award graduate student division, American Society for Pharmacology and Experimental Therapeutics
3. 2nd place poster award Dolores C Shockley division, American Society for Pharmacology and Experimental Therapeutics
4. Selected Graduate Student Abstract Speaker Awardee, Great Lakes Drug Metabolism and Disposition Conference
5. Early career investigator travel award, Society for Neuroimmune pharmacology
6. Travel award, International Society for the Study of Xenobiotics
7. Genentech DMPK Graduate Student/Post Doc Symposium Awardee

Presentations:

1. Poster Presentation; Great Lakes Drug Metabolism and Disposition Group, University of Michigan; April 2023; Ann Arbor, Michigan
2. Poster Presentation; Brain Barriers Meeting at Cold Spring Harbor Laboratory; March 2023; Cold Spring Harbor, New York
3. Poster Presentation; International Conference on Cytochrome P450 and the Annual Meeting of the Japanese Society for the Study of Xenobiotics; September 2023; Shizuoka, Japan
4. Poster and Oral Presentations; Conference for the Society on NeuroImmune Pharmacology. March 2024; Charleston, South Carolina
5. Oral Presentation; Great Lakes Drug Metabolism and Disposition Group, University of Michigan; May 2024; LaFayette, Indiana
6. Oral Presentation; Genentech Graduate Student/Post-Doc DMPK Symposium; April 2024, San Francisco, California
7. Poster and Oral Presentation; American Society on Pharmacology and Experimental Therapeutics (ASPET). May 2024; Washington D.C.
8. Poster and Oral Presentation; International Society for the Study of Xenobiotics (ISSX). September 2024; Honolulu, Hawaii

Publications:

1. White CJ, Gausepohl AM, Wilkins HN, Eberhard CD, Orsburn BC, Williams DW., 2024, Spatial Heterogeneity of Brain Lipids in SIV-Infected Macaques Treated with Antiretroviral Therapy, J Am Soc Mass Spectrom., 35(2):185-196. doi: 10.1021/jasms.3c00276. PMID: 38288997  PubMed
2. Kufera JT, Armstrong C, Wu F, Singhal A, Zhang H, Lai J, Wilkins HN, Simonetti FR, Siliciano JD, Siliciano RF., 2024, CD4+ T cells with latent HIV-1 have reduced proliferative responses to T cell receptor stimulation, J Exp Med., 221(3):e20231511. doi: 10.1084/jem.20231511. PMCID: PMC10818065  PubMed
3. Colón Ortiz R, Knerler S, Fridman LB, Mercado A, Price AS, Rosado-Franco JJ, Wilkins H, Flores BR, Orsburn BC, Williams DW., 2024, Cocaine regulates antiretroviral therapy CNS access through pregnane-x receptor-mediated drug transporter and metabolizing enzyme modulation at the blood brain barrier, Fluids Barriers CNS, 21(1):5. doi: 10.1186/s12987-023-00507-3. PMCID: PMC10777548  PubMed
4. Wheeler AM, Eberhard CD, Mosher EP, Yuan Y, Wilkins HN, Seneviratne HK, Orsburn BC, Bumpus NN., 2023, Achieving a Deeper Understanding of Drug Metabolism and Responses Using Single-Cell Technologies, Drug Metab Dispos., 51(3):350-359. doi: 10.1124/dmd.122.001043. PMCID: PMC10029823  PubMed
5. Suria, A.M.; Smith, S.; Speare, L.; Chen, Y.; Chien, I.; Clark, E.G.; Krueger, M.; Warwick, A.M.;Wilkins, H.; and Septer, AN. Prevalence and diversity of type VI secretion systems in a model beneficial symbiosis. Microbiol. 2022, 13:988044

Fun facts:

1. I enjoy running, practicing embroidery, and spending time with my cat Leucine (who is named after the amino acid)