José “Javier” Rosado-Franco, PhD

Postdoctoral Fellow
José “Javier” Rosado-Franco, PhD

Contact Information

Email
jose.javier.rosado-franco@emory.edu
Education:
  • BSc in Biology, University of Puerto Rico Cayey
  • PhD in Biomedical Sciences, University of Puerto Rico Medical Sciences Campus
Description of research project:
  1. My primary research project focuses on elucidating the possible anti-inflammatory and neuroprotective effects of Cannabidiol (CBD) in an HIV monkey model using Rhesus macaques. Furthermore, I’m interested in determining the changes in microbiota caused by CBD in these animals.
  2. Another project that I’m working on is elucidating the molecular effects and changes in the microbiota caused by HIV pre-exposure prophylaxis using Rhesus macaques.
  3. A side project that I’m working on is determining the microbiota changes caused by THC self-administration in Sprague-Dawley female rats and the crosstalk between the Endocannabinoid system and the Immune system.
Awards:
  1. Center for AIDS Research at Emory University T32 training grant
  2. NIDA Postdoctoral Diversity Scholar
  3. Carl Storm Underrepresented Minority Fellowship Award
Honors:
  1. Recognition by the Deanship of Biomedical Sciences for Academic Excellence, Excellence in Research, Leadership and Honorific Mention for Outreach Activities.
Presentations:
  1. Good Mental Hygiene: Near-Peer Mentor PREP Program-Johns Hopkins University
  2. Exploring the Endocannabinoid System as a new target to treat diseases: Neuroboricuas UPR-Cayey
  3. Innovations on the Road Towards Sepsis Management: Microbiology and Medical Zoology Department, University of Puerto Rico-Medical Sciences Campus
  4. Cannabidiol as a Modulator of Chronic Inflammation During HIV Infection: Endocannabinoid Gordon Research Seminar, Ventura California
  5. Innovations on the Road Towards Sepsis Management: Microbiology and Medical Zoology Department, University of Puerto Rico-Medical Sciences Campus
  6. Back to the Basics: Using our Ancestors Old Tenants to Treat Modern Diseases: Microbiology and Medical Zoology Department, University of Puerto Rico-Medical Sciences Campus
  7. From UPR-Cayey to Grad School: Seminar at University of Puerto Rico at Cayey
  8. CRISPR/Cas9 system: A Milestone in Molecular Biology: Microbiology and Medical Zoology Department, University of Puerto Rico-Medical Sciences Campus
  9. Fasciola hepatica: a pharmacopeia of anti-inflammatory compounds: Center for Tropical Diversity
  10. Fasciola hepatica: a pharmacopeia of anti-inflammatory compounds: Eli Lilly Technical Forum 2019, Puerto Rico Convention Center
  11. Cloning, Expression and Mutagenesis of the hPLAT Gene as a Cheaper and More Effective Treatment for Cardiovascular DiseasesRISE Program at UPR-Cayey
Publications:
  1. Rosado-Franco JJ, Ellison A, White CJ, Price AS, Moore C, Williams R, Fridman LB, Weerts E, Williams DWW. Roadmap for the Expression of Canonical and Expanded Endocannabinoid System Receptors in Metabolic and Immune Peripheral Organs of Pre-Clinical Animal Models. AJP-Regulatory and Integrative Comparative Physiology. Manuscript under review. PMID: 37333264 PMCID: PMC10274867 DOI: 1101/2023.06.10.544455
  2. Colón Ortiz R, Knerler S, Fridman LB, Mercado A, Price AS, Rosado-Franco JJ, Wilkins H, Flores BR, Orsburn BC, Williams DW. Cocaine regulates antiretroviral therapy CNS access through pregnane-x receptor-mediated drug transporter and metabolizing enzyme modulation at the blood brain barrier. Fluids Barriers CNS. 2024 Jan 10;21(1):5. doi: 10.1186/s12987-023-00507-3. PMID: 38200564; PMCID: PMC10777548.
  3. Rosado-Franco JJ, Armina-Rodriguez A, Marzán-Rivera N, Burgos A, Spiliopoulos N, Dorta-Estremera S, Mendez L, Espino A. Recombinant Fasciola hepatica Fatty Acid Binding Protein (Fh15) as a Novel Anti-inflammatory Biotherapeutic in an Acute Gram-negative Non-Human Primate Sepsis Model. Microbiology Spectrum. 2021.
  4. Rosado-Franco JJ, Ramos-Benitez MJ, Parodi LM, Rosario D, Compo N, Giavedoni LD, Espino AM. Outlining key inflammation-associated parameters during early phase of an experimental gram-negative sepsis model in rhesus macaques (Macaca mulatta). Animal Model Exp Med. 2019 Oct 8;2(4):326-333. doi: 10.1002/ame2.12087. PMID: 31942564; PMCID: PMC6930987. *Equal contributors
  5. Ramos-Benitez MJ, Ruiz-Jimenez C, Rosado-Franco JJ, Ramos-Pérez WD, Mendez LB, Osuna A, Espino AM. Fh15 Blocks the Lipopolysaccharide-Induced Cytokine Storm While Modulating Peritoneal Macrophage Migration and CD38 Expression within Spleen Macrophages in a Mouse Model of Septic Shock. mSphere. 2018 Dec 19;3(6):e00548-18. doi: 10.1128/mSphere.00548-18. PMID: 30567900; PMCID: PMC6300687.
  6. Zha X, Diaz R, Rosado-Franco JJ, Sanchez VF, Fasoli E, Barletta G, Carvajal A, Bansal V. Inhibitors of urokinase type plasminogen activator and cytostatic activity from crude plants extracts. Molecules. 2013 Jul 26;18(8):8945-58. doi: 10.3390/molecules18088945. PMID: 23896619; PMCID: PMC4034058.
Fun facts:
  1. I also employ the scientific method in my cooking and baking
  2. I refuse to consider myself to be an adult yet
  3. I love animals more than humans
  4. I consider my dog to be my son
  5. I prefer to go to the beach at night